Thermo Scientific™ TSQ Altis™ Plus EFOX Edition is a triple quadrupole mass spectrometer specifically developed for highly sensitive targeted LC-MS/MS analysis of food and environmental samples. It combines high selectivity, rapid data acquisition, and robust performance in complex matrices for reliable quantitation of trace contaminants.
QR5 Plus segmented quadrupole mass filters with hyperbolic surfaces provide efficient ion transmission and selection. H-SRM operation at mass window widths down to 0.2 Da FWHM helps distinguish target analytes from interfering compounds and can improve signal-to-noise ratios. The OptaMax™ NG ion source supports HESI and APCI, providing flexibility across different compound classes.
Dual-CID technology expands method development capabilities through sequential fragmentation processes that generate additional MS³-like fragment ions. This provides greater flexibility when selecting and optimizing analytical transitions for compounds where conventional MS/MS fragmentation does not offer sufficient selectivity.
Automated compound optimization and integration with the mzCloud™ database simplify targeted method development. Chromeleon™ Chromatography Data System (CDS) brings together instrument control and data processing, while adjustable transition dwell times support efficient data acquisition in multi-compound methods.
Combined with Vanquish™ UHPLC systems, including Vanquish Flex Duo dual-channel configurations, EFOX Edition supports integrated workflows for PFAS, pesticides, and other contaminants. The solution is suitable for routine testing laboratories as well as the development of specialized analytical methods.
| Parameter | Specification |
|---|---|
| Mass range | m/z 2–2010. |
| Q1 and Q3 resolution | Adjustable peak widths down to 0.2 Da FWHM across the mass range. |
| SRM acquisition rate | Up to 800 SRM transitions/s.* |
| Number of definable SRM transitions | Up to 30,000, with timed acquisition available. |
| Scan speed | 15,000 amu/s at 2 Da FWHM. |
| Polarity switching | 5 ms, including signal stabilization. |
| Linear dynamic range | Greater than six orders of magnitude. |
| Ion source | OptaMax NG, supporting HESI and APCI. |
| Mass spectrometer dimensions | 840 × 760 × 680 mm — depth × width × height. |
| Mass spectrometer weight | 125 kg. |